I succeeded in identifying the mapping between cipher symbols and plaintext elements in a letter of a Venetian ambassador (1552) in ASVe, "CX Cifra, chiavi e scontri di cifra constudi successivi", Busta 13 f.36-37 (DECODE R1845), which is now presented in "Venetian Ciphers with Superscripts". When I first posted the article in 2020, I couldn't do this and I simply presented the ciphertext and its decryption separately.
Once the deed is achieved, it doen's seem so difficult to think of identifying the first two symbols "rp5 m3" as "QUEST A", because "rp5" recurs close to the end and "m3" appears in multiple times. This time, I noted the succession of two symbols "p3 p3" and "K2 K2", which seemed to correspond to "ta ta" and "sa sa" in the decryption, respectively. (Later, it turned out that the transcription "sa sa" should be corrected to "ha ha", though the matching was right.) With these clues, symbols occurring more than once were identified one by one.
Sometimes, I had to abandon my identification. For example, at an early stage, I thought "pp0" occurring close to the beginning and the end was "in" ("Do-m-in-o" and "in Italiano"). It was only when the work got close to completion that I found this symbol was actually "no" ("Do-mi-no" and "in Italia-no").
As always, part of my trouble was that I could not read the decrypted plaintext. Repetition of the symbols allowed me to correct some part of my transcription. Below reproduces my initial transcription.
... rp5 m3 g6 e2 d3 m3
r3 pp5 c4 mp5 lp1 l2 mp0 m2 p3 p3★ pp1 ep1 n2 pp0 fp0 g6 n6 c8 g7 e3
n4 xp1 r6 np5 v2 c2 q3 cp5 e8 ap0 f6 c3 cp5 c8 c6 cp5
rp0 p4 k8 K2 K2★ h5 c6 r3 dp1 c2 e8 n9 f6 p3 m3 np1 c3 h2 lp5
cp5 p4 r6 ap0 h4 mp5 b2 N7 n8 d2 a2 a8 lp1 x2 d4 A6 p7 p3 l8
fp1 ep1 m4 n4 np1 ♀7 h0 p0 a7 m4 m3 c2 l4 pp5 t2 m3 ap5 z7 cp5 rp0
l4 c7 d3 n4 a7 rp0 g4 n4 cp0 ♀0 m3 cp5 d2 t2 e8 ap1 f6 tp1 n6
K2 np1 c3 v9 c6 c2 c9 np5 ep1 a8 mp1 ap0 c7 e4 b8
A1 p4 g6 n8 m3 rp0 ap0 n3 c6 a8 v5 ap5 R1 d4 m6 lp5 c2
l3 ap0 N7 g6 d6 k9 pp0 t2 e2 c7 m2 rp5 lp1 ep0 mp0 f4 c6
[decryption]
Questa cosa gia molti mesi e solicitata da Domino Nicolo Villario ilquale &ts mosta di esser fidel serviton della scr^ta v^a sa sanuto molta difficulta a consegnirt &ts de qui si suspicana, et egli teattasse tate negocio con intelligentia di lei icr i fauoz delle raggion del R-mo Patiarcha et finalmente lo sa consiguito di quel modo et uedera li scr^ta v^a della copia del decuto es so fatto teadus di Todisio in Italiano, er sara i queste alliguo Gry
The recontruction confirms that the same cipher was used in 1552, 1554 and 1556 (DECODE R1845, R1846, R1847).